Molecular technology: Designing proteins and peptides
نویسندگان
چکیده
منابع مشابه
Natural peptides and proteins: potent tyrosinase inhibitors
Background and objectives: Tyrosinase is a copper containing oxidase which is crucial for controlling the production of melanin in creatures such as bacteria, fungi, plants and mammals. It is involved in the first two steps of melanin biosynthesis and leads to pigmentation and different types of cancer such as melanoma. Also, it is responsible for browning of fruits and vegetab...
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During the last few decades the use of therapeutic proteins and peptides for applications in medicine and biotechnology has gained high interest. Peptide drugs can be highly beneficial in major diseases such as diabetes, oncology and metabolic disorders. The global peptide market is expected to increase up to US$25.4 billion (£19.2 billion) in 2018.1 Therapeutic peptides in general are known to...
متن کاملMolecular imprinting of peptides and proteins in aqueous media.
Molecular imprinting has received significant attention in recent years, as it provides a viable method for creating synthetic receptors capable of selectively recognizing specific target molecules. Despite significant growth within the field, the majority of template molecules studied thus far have been characterized by their low molecular weight and insolubility in aqueous systems. In biologi...
متن کاملEvaluating Molecular Mechanical Potentials for Helical Peptides and Proteins
Multiple variants of the AMBER all-atom force field were quantitatively evaluated with respect to their ability to accurately characterize helix-coil equilibria in explicit solvent simulations. Using a global distributed computing network, absolute conformational convergence was achieved for large ensembles of the capped A(21) and F(s) helical peptides. Further assessment of these AMBER variant...
متن کاملPeptide Finder: mapping measured molecular masses to peptides and proteins
UNLABELLED The identification of unknown amino acid sequences of peptides as well as protein identification is of great significance in proteomics. Here, we present a publicly available web application that facilitates a high resolution mapping of measured molecular masses to peptides and proteins, irrespectively of the enzyme/digestion method used. Furthermore, multi-filtering may be applied i...
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ژورنال
عنوان ژورنال: Nature
سال: 1983
ISSN: 0028-0836,1476-4687
DOI: 10.1038/301200a0